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Predictor of Complications After Coronary Shunting

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Research Article | DOI: https://doi.org/10.31579/2835-785X/123

Predictor of Complications After Coronary Shunting

  • Maksimovich Yelizaveta ID *

Department of Propaedeutics of Internal Medicine, Grodno State Medical University, Grodno, Belarus.

*Corresponding Author: Dr. Maksimovich Yelizaveta, Department of Propaedeutics of Internal Medicine, Grodno State Medical University, Grodno, Belarus.

Citation: Maksimovich Yelizaveta, (2026), Predictor of Complications After Coronary Shunting, International Journal of Clinical Research and Reports. 5(2); DOI: 10.31579/2835-785X/123.

Copyright: © 2026, Dr. Maksimovich Yelizaveta. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Received: 07 February 2026 | Accepted: 20 February 2026 | Published: 03 March 2026

Keywords: complications; hemolysis; iron; CABG; IOH; coronary shunting

Abstract

Purpose. It was to study the role of iron in the development of complications of coronary artery bypass surgery (CABG) in patients with coronary artery disease.

Methods. In accordance with [Hb] In the blood plasma, patients with CABG surgery are divided into 3 groups: 1 – without IOH (Hb≤0.1 g/l), n=43, 2 – with low IOH (lIOH) - Hb>0.1 g/l and <0.5 g/l, n=42, 3 – with high IOH (hIOH) Hb≥0.5g/l, n=38. Determined serum iron - [Fe2+], transferrine (Tr), Tr saturation coefficient (TSC), total serum iron-binding capacity (TSIBC), latent iron-binding capacity of blood, LIBC, ferritin (F) (Mindray BS-200). The complications of cardiovascular (C) genesis were detected. Statistical processing was carried out using the program STATISTICA 10.0.

Results. The most significant differences of the studied parameters at the end of the CABG compared with their initial value, were observed in patients (P) with IOH - an increase in [Fe2+] by 91.9%, TSC – by 87.3%, F – by 165.9% and a decrease in the level of Tr – by 22.0% and LIBC – by 45.0% p<0.001. In the P group with lIOH, the changes were less pronounced (p<0.001), and in the group without IOH there were no changes (p>0.05). The presence of C was observed in 23.6 of P, p<0.001. The highest frequency of C was observed in the group with hIOH (57.9% P, p<0.001), in the group with lIOH – in 5 (11.9% P, p<0.001), and in the group without IOH – only 4.7% P, p<0.001). There were associations (rs) with the frequency of C and TSC – 0.57, F - 0.57, LIBC – -0.56, [Fe2+] – 0.55, Tr – -0.49.

Conclusions. The presence of complications of CABG mainly in patients of the group with the hIOH, the nature of changes in indicators of transport and deposited iron pools, as well as the presence of associations of the frequency of complications with these indicators indicate the involvement of free iron in their development.

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