Review Article | DOI: https://doi.org/10.31579/2835-8325/155
Right of the Following Statements about how many times you can always get Over Hormones in Food
- Fahim Aziz Eldein Shaltout *
Department of Food Hygiene and Control (Meat hygiene), Faculty of Veterinary Medicine, Benha University, Benha 13736, Egypt.
*Corresponding Author: Fahim Aziz Eldein Shaltout, Department of Food Hygiene and Control (Meat hygiene), Faculty of Veterinary Medicine, Benha University, Benha 13736, Egypt.
Citation: Eldein Shaltout FA, (2025), Right of the Following Statements about how many times you can always get Over Hormones in Food, Clinical Research and Clinical Reports, 7(4); DOI: 10.31579/2835-8325/155
Copyright: © 2025, Fahim Aziz Eldein Shaltout. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Received: 12 March 2025 | Accepted: 26 June 2025 | Published: 15 April 2025
Keywords: hormonal residues; growth promoters; livestock production; potential risks
Abstract
Hormonal residues in meat have become a growing concern due to their potential health and environmental impacts. These residues result from the use of hormonal growth promoters (HGPs) in livestock production, which are employed to enhance growth rates, improve feed efficiency, and increase meat yield. This paper explores the sources, detection methods, regulatory measures, and potential risks associated with hormonal residues in meat products.
Introduction
The global demand for meat has led to intensified livestock production systems (1-7). Hormonal growth promoters, such as estrogen, progesterone, and synthetic anabolic steroids, are commonly used to accelerate growth in cattle, poultry, and swine (8-15). While these practices improve economic efficiency, they raise concerns about hormonal residues entering the food chain (144-150). potentially affecting human health and environmental systems (151-156).
Sources of Hormonal Residues
Hormonal residues in meat originate from Natural Hormones (137-143). Produced endogenously by animals (16-23). Synthetic Hormones, administered to enhance growth and productivity, such as trenbolone acetate, zeranol, and melengestrol acetate (24-30). Mismanagement, Overuse or improper withdrawal periods before slaughter can lead to residue accumulation (31-37).
Detection of Hormonal Residues
Modern techniques have advanced the detection of hormonal residues in meat as Enzyme-Linked Immunosorbent Assay (ELISA), Used for rapid and cost-effective screening (38-44). Gas Chromatography-Mass Spectrometry (GC-MS) Offers high sensitivity and specificity (45-51). High-Performance Liquid Chromatography (HPLC): Common for quantifying hormone levels (52-58).
Health Implications
Endocrine Disruption: Residues may interfere with hormone receptors, leading to reproductive and developmental issues (59-65). Carcinogenic Risks, Long-term exposure to some hormones is linked to increased cancer risks (66-72). Antibiotic Resistance, Hormone treatments often coincide with antibiotic use, compounding public health challenges (73-79).
Regulations and Standards
Regulatory frameworks differ globally (130-136). European Union (EU) Prohibits hormonal growth promoters in livestock. United States (FDA/USDA) Permits limited use under strict guidelines. Codex Alimentarius Provides international food standards, including Maximum Residue Limits (MRLs) (80-86).
Environmental Concerns
Hormonal residues excreted by livestock can contaminate water systems, affecting aquatic organisms and ecosystems (87-93). Studies show hormonal disruption in fish populations near livestock farming areas, highlighting the broader ecological impact (94-100).
Mitigation Strategies
1. Improved Livestock Management, Adhering to withdrawal periods and monitoring feed additives (101-108). Alternative Growth Promoters, Using probiotics, enzymes, or plant-based additives (109-115). Policy Enforcement: Strengthening inspections and penalties for non-compliance (116-122). Hormonal residues in meat remain a contentious issue, balancing economic benefits against potential health and environmental risks (123-129).
Conclusion
Advances in detection methods and stricter regulations are critical to ensuring food safety and sustainability. Collaborative efforts among scientists, policymakers, and industry stakeholders are essential to mitigate risks and protect public health.
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View at Publisher | View at Google Scholar - Shaltout,F.A., Amin, R., Marionet, Z., Nassif and Shimaa, Abdel-wahab (2014): Detection of aflatoxins in some meat products. Benha veterinary medical journal, 27(2) :368-374.
View at Publisher | View at Google Scholar - Shaltout, F. A.; Eldiasty , E. and Mohamed, M.S. (2014): Incidence of lipolytic and proteolytic fungi in some chicken meat products and their public health significance. Animal Health Research Institute: First International Conference on Food Safety and Technology 19-23 June 2014 Cairo Egypt pages 79-89.
View at Publisher | View at Google Scholar - Shaltout, F.A.; Eldiasty, E.; Salem, R. and Hassan, Asmaa (2016): Mycological quality of chicken carcasses and extending shelf – life by using preservatives at refrigerated storage. Veterinary Medical Journal -Giza (VMJG)62(3)1-7.
View at Publisher | View at Google Scholar - Shaltout, F.A.; Salem, R. Eldiasty, E.; and Diab, Fatema. (2016): Mycological evaluation of some ready to eat meat products with special reference to molecular chacterization. Veterinary Medical Journal -Giza 62(3)9-14.
View at Publisher | View at Google Scholar - Shaltout, F. A.; El Shater, M. and Wafaa, Abdelaziz (2015): Bacteriological assessment of street vended meat products sandwiches in Kalyobia Governorate. Benha Vet. Med.J.28 (2):58-66.
View at Publisher | View at Google Scholar - Shaltout, F. A.; Gerges, M.T. and Shewail, A.A. (2018): Impact of Organic Acids and Their Salts on Microbial Quality and Shelf Life of Beef. Assiut veterinary medical journal 64(159): 164-177
View at Publisher | View at Google Scholar - Shaltout, F.A.; Hashim,M.F. and Elnahas,s.(2015): Levels of some heavy metals in fish (tilapia nilotica and Claris lazera) at Menufia Governorate. Benha Vet. Med.J.29 (1):56-64.
View at Publisher | View at Google Scholar - Shaltout,F.A. and Ibrahim, H.M. (1997): Quality evaluation of luncheon and Alexandrian sausage. Benha Vet. Med.J.10 (1):1-10.
View at Publisher | View at Google Scholar - Shaltout, F.A.; Nassif, M and Shakran, A (2014): Quality of battered and breaded chicken meat products. Global Journal of Agriculture and Food Safety Science – 1(2) ISSN 2356-7775.
View at Publisher | View at Google Scholar - Shaltout,F.A., Amani M. Salem, A. H. Mahmoud, K. A (2013): Bacterial aspect of cooked meat and offal at street vendors level. Benha veterinary medical journal, 24(1): 320-328.
View at Publisher | View at Google Scholar - Shaltout,F.A. and Salem, R.M. (2000): Moulds, aflatoxin B1 and Ochratoxin A in Frozen Livers and meat products.Vet . Med. J.Giza 48(3):341-346.
View at Publisher | View at Google Scholar - Yasser H. Al-Tarazi, A. Al-Zamil, Shaltout FA. and H. Abdel- Samei (2002). Microbiological status of raw cow milk marketed in northern Jordan. AVMJ Volume 49 Issue 96 Pages 180-194
View at Publisher | View at Google Scholar - Shaltout FA, Zakaria IM and Nabil ME. (2018): Incidence of Some Anaerobic Bacteria Isolated from Chicken Meat Products with Special Reference to Clostridium perfringens. Nutrition and Food Toxicology2(5):429-438.
View at Publisher | View at Google Scholar - Shaltout, F. A.; El-diasty, E.M. and Mohamed, M. S. (2014): Incidence of lipolytic and proteolytic fungi in some chicken meat products and their public health significance. 1st Scientific conference of food safety and Technology .2014, pp. 79-89.
View at Publisher | View at Google Scholar - Shaltout, F. A.; El-diasty, E.M.; Salem, R. M. and Asmaa, M. A. Hassan. 2016: Mycological quality of chicken carcasses and extending shelf -life by using preservatives at refrigerated storage. Veterinary Medical Journal – Giza ,62(3) :1-10.
View at Publisher | View at Google Scholar - Shaltout FA, R.M. Salem, E.M. El-Diasty and W.I.M. Hassan. 2019: Effect of Lemon Fruits and Turmeric Extracts on Fungal Pathogens in Refrigerated Chicken Fillet Meat. Global Veterinaria 21 (3): 156-160,
View at Publisher | View at Google Scholar - Shaltout FA, El-diasty, E, M.; Elmesalamy, M. and Elshaer, M. (2014): Study on fungal contamination of some chicken meat products with special reference to 2 the use of PCR for its identification. Conference, Veterinary Medical Journal – Giza vol. December 2014/12/17 vol.60 1-10.
View at Publisher | View at Google Scholar - Shaltout, F. A.; Salem, R. M; El-diasty, Eman and Fatema, A.H. Diab. (2016): Mycological evaluation of some ready to eat meat products with special reference to molecular characterization. Veterinary Medical Journal – Giza. 62(3): 9-14.
View at Publisher | View at Google Scholar - Shaltout FA, Ahmed, A.A. Maarouf, Eman, M.K. Ahmed (2018): Heavy Metal Residues in chicken cuts up and processed chicken meat products. BENHA VETERINARY MEDICAL JOURNAL, 34(1): 473-483.
View at Publisher | View at Google Scholar - Shaltout, F.A.; Hanan M. Lamada , Ehsan A.M. Edris. (2020): Bacteriological examination of some ready to eat meat and chicken meals. Biomed J Sci & Tech Res., 27(1): 20461- 20465.
View at Publisher | View at Google Scholar - Sobhy, Asmaa and Shaltout, Fahim (2020): Prevalence of some food poisoning bacteria in semi cooked chicken meat products at Qaliubiya governorate by recent Vitek 2 compact and PCR techniques. Benha Veterinary Medical Journal 38 (2020) 88-92.
View at Publisher | View at Google Scholar - Shaltout, F. A. (2024): Good Idea on Preservatives and the Natural Preservatives and Meat Preservation Against the Foodborne Pathogens and the Spoilage Microorganisms. Biomed J Sci & Tech Res 57(5)-2024. BJSTR. MS.ID.009067.
View at Publisher | View at Google Scholar - Sobhy, Asmaa and Shaltout, Fahim (2020): Detection of food poisoning bacteria in some semi-cooked chicken meat products marketed at Qaliubiya governorate. Benha Veterinary Medical Journal 38 (2020) 93-96.
View at Publisher | View at Google Scholar - Shaltout, F.A. (2024): Abattoir and Bovine Tuberculosis as A Reemerging Foodborne Diseas. Clinical Medical Reviews and Report 6(1):1-7.
View at Publisher | View at Google Scholar - Shaltout, F.A. (2023): Viruses in Beef, Mutton, Chevon, Venison, Fish and Poultry Meat Products. Food Science & Nutrition Technology 8(4):1-10.
View at Publisher | View at Google Scholar - Shaltout, F. A. (2024): Human Salmonellosis Acquired through the Food
View at Publisher | View at Google Scholar - Elkholy, R. A; Hussein, M. N; Abou El-Roos, N. A. and Shaltout, F.A.E. (2025) Enhancing Microbiological and Histological Quality of Frozen Turkey Meat Using Vinegar. Egyptian Journal of Veterinary Sciencespp 1-8. DOI: 10.21608/EJVS.2024.291707.2118
View at Publisher | View at Google Scholar - Shaltout, F. A. (2024): Availability, Price, Tradition, Religion, Income, Social, Development and Economic Influences on Meat Consumption. Med J Clin Trials Case Stud 2024, 8(2): 000370
View at Publisher | View at Google Scholar - Mohamed Q. M., Fahim A. Shaltout, f.A. and Ali, E.A. (2025): Multidrug-Resistant Bacteria from Raw Chevon and Mutton Meat. Egyptian Journal of Veterinary Sciences pp 1-8. DOI: 10.21608/EJVS.2024.310881.2302
View at Publisher | View at Google Scholar - Shaltout, F. A. E; Ab delazez Ahmed Helmy Barr, Mohamed Elsayed Abdelaziz. .(2024): Pathogenic Microorganisms in Meat Products. Biomed J Sci & Tech Res 41(4)-2022. BJSTR. MS.ID.006623.
View at Publisher | View at Google Scholar - Mohamed Q. M., Fahim A. Shaltout, f.A. and Ali, E.A. (2025): Bacteriological Quality Profiles and Prevalence of Staphylococcus aureus, Salmonella Species, and E. coli in Meat Samples of Sheep and Goats. Egyptian Journal of Veterinary Sciences pp 1-7. DOI: 10.21608/EJVS.2024.312380.2317
View at Publisher | View at Google Scholar - Ibrahim, S. M.; Hassanin, F. S.; Abou-Elroos, N. S. and Shaltout, F.A (2025): Quantifying The antimicrobial Efficacy of Selected Herbal Essential Oils Against Bacteria in Simulated Beef Steak Conditions. Egyptian Journal of Veterinary Sciences, pp 1-9. DOI: 10.21608/EJVS.2024.329367.2437
View at Publisher | View at Google Scholar - Shaltout, F. A. (2024): The Availa bility, the Price, the Tradition, the Reli gion, the Income, the Social, the Develop ment and the Economic Influences on the Meat Consumption. Biomed J Sci & Tech Res 55(4)-2024. BJSTR. MS.ID.008734.
View at Publisher | View at Google Scholar - Ibrahim, S. M.; Hassanin, F. S.; Abou-Elroos, N. S. and Shaltout, F.A (2025): Evaluating The impact of Certain Herbal Essential Oils on The Shelf Life and Chemical Composition of Beef Steak. Egyptian Journal of Veterinary Sciences, pp. 1-8. DOI: 10.21608/EJVS.2024.329509.2439
View at Publisher | View at Google Scholar - Shaltout, F. A. (2024): Our Opinion on Using of Irradiation in Food Preservation and Production. Journal of Medical and Clinical Case Reports, 1(6): 1-9. https://doi.org/10.61615/JMCCR/2024/AUG027140805
View at Publisher | View at Google Scholar - Anees, K. P; El-diasty, E. M. and Shaltout, F. A. (2023): Mycological Evaluation and Occurrence of Aflatoxins and Ochratoxin A in Tilapia Oreochromis niloticus Fish and Fish Products. Journal of Advanced Veterinary Research ,13(7):1381-1385.
View at Publisher | View at Google Scholar - AMR, A. K; HASSANIN, F. S.; HASSAN, M. A. and SHALTOUT, F. A. E. (2024): TRIALS TO ESTIMATE AND CONTROL THE RESIDUAL LEVELS OF HETEROCYCLIC AROMATIC AMINES IN MEAT PRODUCTS. Assiut Vet. Med. J., 70 (182): 98-105.
View at Publisher | View at Google Scholar - Shaltout, F. A.; Mohammed, I.; Afify, E. A. (2020): Detection of E. coli O157 and Salmonella species in some raw chicken meat cuts in Ismailia province, Egypt. Benha Veterinary Medical Journal 39(2): 101-104.
View at Publisher | View at Google Scholar - Hassanin, F. S.; Shaltout, F. A.; Maarouf, A. A.; El-Sisy, S. F.; Ahmed, A. E. (2020): Bacteriological profile of frozen chicken meat cuts at Qalubiya governorate markets. Benha Veterinary Medical Journal 39 (2) 1-5.
View at Publisher | View at Google Scholar - Shaltout, F. A.; Heikal, G. I.; Ghanem, A. M. (2022): Mycological quality of some chicken meat cuts in Gharbiya governorate with special reference to Aspergillus flavus virulent factors. Benha Veterinary Medical Journal 40 (42) 12-16.
View at Publisher | View at Google Scholar - Shaltout, F. (2024) Application of Irradiation in Food Preservation and Production. Journal of Pathology Research Reviews & Reports. SRC/JPR-190. 6(5): 1-8. DOI: doi.org/10.47363/JPR/2024(6)173
View at Publisher | View at Google Scholar - Taha, S. T.; Shaltout, F. A.; Shimaa, N. Edris, S. N.; Mohamed, E. Nabil, M. E. (2024): Effect of lavender oil, clove oil and frankincense extract on sensory and microbial properties of raw drumsticks in refrigerator. Benha Veterinary Medical Journal 46 (1) 135-139.
View at Publisher | View at Google Scholar - Shaltout, F. A.; Salem, R. M; Eldiasty, E. M and Diab, F. A. (2023): Experimental Study on the Effect of Propionibacterium and Acetic acid on Candida albicans contamination in chicken fillet Stored at Chilling Conditions. Benha Veterinary Medical Journal 43 (2) 91-96.
View at Publisher | View at Google Scholar - Mubarak, S. R.; Abou EL-Roos, N. A.; Hussein, M. N. and Shaltout, F. A. E. (2024): Comparative microbiological evaluation between fresh and frozen bovine liver. Benha Veterinary Medical Journal 47 (1) 99-102.
View at Publisher | View at Google Scholar - El Asely,M. M.; Fath Elbab, G. F.; Shaltout, F. A. E. (2024): Antibiotic Residues in Commercially Available Freshwater and Marine Fish: A Risk Assessment. Egyptian Journal of Aquatic Biology & Fisheries, 28(1): 397 – 410.
View at Publisher | View at Google Scholar - El Asely, M. M.; Fath Elbab, G. F. and Shaltout, A. E. (2025): Impact of Freezing Intervals on Oxytetracycline and Ciprofloxacin Residues in Nile Tilapia and Catfish Muscles. Egypt. J. Vet. Sci. Vol. 56, No. 7, pp. 1419-1424. DOI: 10.21608/EJVS.2024.278904.1962
View at Publisher | View at Google Scholar - Elkholy, R. A.; Abou EL-Roos, N. A.; Hussein, M. N. and Shaltout, F. A. E. (2025): Differential Microbiological Quality on Marketed Frozen Turkey Breast and Thigh Meat. Egypt. J. Vet. Sci. 56, (1), pp. 1-10. DOI: 10.21608/EJVS.2024.266925.1816.
View at Publisher | View at Google Scholar - Shaltout, F. A. (2024): THE FOOD ADDITIVES USED IN FOOD PRODUCTION, ADVANTAGES AND DISADVANTAGES. World Journal of Internal Medicine and Surgery 1(6): 1-17
View at Publisher | View at Google Scholar - Shaltout, F. A. (2024): Right Methods to Extend the Meat Shelf- Life by Using of Natural Preservatives and Their Public Health Importance. Journal of Medicine Care and Health Review 1(2): 1-17. https://doi.org/10.61615/JMCHR/2024/SEPT027140921
View at Publisher | View at Google Scholar - Saad M. Saad, Fahim A. Shaltout, Amal A. A. Farag & Hashim F. Mohammed (2022): Organophosphorus Residues in Fish in Rural Areas. Journal of Progress in Engineering and Physical Science 1(1): 27-31. doi:10.56397/JPEPS.2022.11.05
View at Publisher | View at Google Scholar - Shaltout, F. A. (2024): Importance of Extending the Shelf Life of the Meat. Journal of Medical and Clinical Case Reports 01 |(9): 1-10. https://doi.org/10.61615/JMCCR/2024/SEPT027140902
View at Publisher | View at Google Scholar - Shaltout, F. A. E., Mona N. Hussein, Nada Kh. Elsayed (2023): Histological Detection of Unauthorized Herbal and Animal Contents in Some Meat Products. Journal of Advanced Veterinary Research (2023) 13(2): 157-160.
View at Publisher | View at Google Scholar - Shaltout, F. A (2023): Abattoir and Bovine Tuberculosis as A Reemerging Foodborne Disease. Clinical Medical Reviews and Reports 6(1): 1-7 DOI: 10.31579/2690-8794/189
View at Publisher | View at Google Scholar - Shaltout, F. A., Ramadan M. Salem, Eman M. Eldiasty, Fatma A. Diab (2022): Seasonal Impact on the Prevalence of Yeast Contamination of Chicken Meat Products and Edible Giblets. Journal of Advanced Veterinary Research ,12(5):641-644.
View at Publisher | View at Google Scholar - Shaltout, S. and Shaltout,F. (2024), “Food Borne Bacterial Diseases Due to Consumption of Meat, Fish and Poultry Products”, Arch Health Sci; 8(1): 1-8. DOI: 10.31829/2641-7456/ahs2024-8(1)-004
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View at Publisher | View at Google Scholar - Hakeem, K. P.; El-diasty, E. M.; Shaltout, F. A. E. (2023): Effects of natural compounds of some plants on microbial contamination and sensory quality of fish fillet during refrigeration. Benha Veterinary Medical Journal 45 (1) 152-156.
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