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Short Communication | DOI: https://doi.org/10.31579/2835-835X/095

Mortality due to tetanus

  • Yaser Kaplan
  • Burak Cilli
  • Ali Bucak,
  • Anıl Yoldaş
  • Ali Karakus

Hatay Mustafa Kemal University, Faculty of Medicine, Emergency Medicine, Hatay, Turkey.

*Corresponding Author: Ali Karakus, Hatay Mustafa Kemal University, Faculty of Medicine, Department of Emergency Medicine.

Citation: Yaser Kaplan, Burak Cilli, Ali Bucak, Anıl Yoldaş, Ali Karakus, (2025), Mortality due to tetanus, Clinical Trials and Case Studies, 4(1); DOI:10.31579/2835-835X/095

Copyright: © 2025, Ali Karakus. This is an open-access artic le distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Received: 01 November 2024 | Accepted: 02 December 2024 | Published: 06 January 2025

Keywords: tetanus; opisthotonus; immunoglobulin; mortality

Abstract

Tetanus is a notifiable disease, with an estimated incidence of approximately 1 million patients per year worldwide and a mortality rate of 20% to 30%. Patients who are thought to have tetanus should be hospitalized and monitored according to their general condition and hemodynamic stability.

 

 

 

 

Introduction

Tetanus is defined as a widespread muscle spasm syndrome characterized by acute hypertonia or painful muscle contractions, usually in the jaw and neck muscles, without other medical causes. Although widespread vaccination programs have caused a decrease of >95% in the annual incidence of tetanus, we wanted to emphasize that patients presenting with these complaints should be careful about the possibility of tetanus. A 62-year-old female patient applied to the emergency department due to complaints of severe pain and contraction in the neck and jaw muscles that had been ongoing for 2 days. Her medical history indicated that she had a nail stuck into the sole of her right foot 15 days ago. The patient, who did not go to any health institution, applied to an external center due to swelling in her foot where the nail was stuck. According to the information received from the patient; the patient, who was vaccinated against tetanus at the external center, was discharged with a prescription for antibiotics. The patient's general condition is good, she is conscious, oriented, cooperative. Her blood pressure was 110/70 mmHg. Pulse: 80/min. Respiration: 14/min. Fever: 36 C. Other physical examination findings showed neck contraction and pain, and no additional pathology was detected. The patient who was considered to have temporomandibular dystonia was given analgesia, and after the patient partially relaxed, he was discharged with the outpatient clinic recommendation. When the patient was brought back 3 days later, he had opisthotonus. The patient, who was admitted to the intensive care unit for infectious diseases, was started on tetanus immunoglobulin and supportive treatment. The patient, who developed respiratory distress during his follow-ups, was started on respiratory support with a mechanical ventilator. The patient, who had cardiopulmonary arrest after 3 days of follow-up in the intensive care unit, was accepted as exitus. In cases brought with complaints of severe pain and contraction in the neck and jaw muscles, speech disorder and jaw locking, tetanus should be considered and the anamnesis should be deepened. Vaccination and tetanus immunoglobulin should be considered according to wound cleaning and the patient's tetanus vaccination prophylaxis status. Immunoglobulin should definitely be administered to cases with dirty wounds and unknown or unknown vaccination schedules.  It should not be forgotten that this syndrome, which has a mortality rate of 30%, can quickly lead the patient to respiratory failure.

References

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